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“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

- Claude Bernard -

Peer-reviewed Original Research Articles

 Peer-reviewed Reviews, Chapters, Monographs, and Editorials   

1.         Polverino F, Santoriello C, De Sio V, Andò F, de Blasio F, Polverino M. Sexual intercourse and respiratory failure. Respir Med. 2008 Jun; 102(6):927-31. PMID: 18394872.

2.         D'Agostino B, Polverino M, Cirino G, Lombardi A, Grassi B, Sullo N, Santoriello C, Polverino F, Orlotti D, Matteis M, Rossi F. Exercise capacity and cytochrome oxidase activity in muscle mitochondria of COPD patients. Respir Med. 2010 Jan; 104(1):83-90. PMID: 19716278.

3.         Cuomo G, Santoriello C, Polverino F, Ruocco L, Valentini G, Polverino M. Impaired exercise performance in systemic sclerosis and its clinical correlations. Scand J Rheumatol. 2010 Aug; 39(4):330-5. PMID: 20476863.

4.         Polverino F, Baraldo S, Bazzan E, Agostini S, Turato G, Lunardi F, Balestro E, Damin M, Papi A, Maestrelli P, Calabrese F, Saetta M. A novel insight into adaptive immunity in COPD: B cell activating factor belonging to the TNF family. Am J Respir Crit Care Med. 2010 Oct 15; 182(8):1011-9. PMID: 20581172.

5.         Polverino M, Polverino F, Fasolino M, Andò F, Alfieri A, De Blasio F. Anatomy and neuro-pathophysiology of the cough reflex arc. Multidiscip Respir Med. 2012 June 18; 7(1):5. PMID: 2295836.

6.         Sullo N, Roviezzo F, Matteis M, Spaziano G, Del Gaudio S, Lombardi A, Lucattelli M, Polverino F, Lungarella G, Cirino G, Rossi F and D’Agostino B. Skeletal muscle oxidative metabolism  in an animal model of pulmonary emphysems: formoterol and skeletal muscle dysfunction. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):198-203. PMID: 23144332. 

7.         Polverino F†, Polverino M, Santoriello C, Palladino R, Ricciardi M, Pistolesi M.  Voice box symptoms: a hitherto unknown presentation of pulmonary embolism. Am J Respir Crit Care Med. 2013 Jan 1;187(1):108-10. PMID: 23281354

8.         Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA. Adam8 limits the development of allergic airway inflammation in mice. J Immunol 2013 Jun 15; 190(12):6434-49. PMID: 23670189. PMCID: PMC3679335.

9.         Iannuzzi A, Licenziati MR, De Michele F, Verga MC, Santoriello C, Di Buono L, Renis M, Lembo L, Cappetta D, Polverino M, Polverino F†. C-reactive-protein and carotid intima-media thickness in children with sleep-disordered breathing. J Clin Sleep Med. 2013 May 15; 9(5):493-8. PMID: 23674941. PMCID: PMC3629324.

10.       Craig, V, Polverino F, Laucho-Contreras M, Shi Y, Liu Y, Osorio J, Tesfaigzi Y, Rosas I, Owen CA. Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (mmp-8) in patients with idiopathic pulmonary fibrosis. PLoS One. 2014 May 14; 9(5):e97485. PMID: 24828408. PMCID: PMC4020836.

11.       Roychaudhuri R, Hergrueter AH, Polverino F, Owen CA. ADAM9 is a novel product of polymorphonuclear neutrophils: subcellular localization, regulation of expression, and contributions to extracellular matrix protein degradation. J Immunol 2014 Sep 1; 193(5):2469-82. PMID:25063875

12.       Cicchitto G, Musella V, Acitorio M, Capuano N, Fiorenzano G, Owen CA, Polverino M, Polverino F†. Idiopathic pulmonary fibrosis and coronary artery disease. Multidiscip Respir Med. 2014 May 30; 9(1):31. PMID: 24976970.

13.       Matteis M*, Polverino F*, Spaziano G, Roviezzo F, Santoriello C, Sullo N, Bucci MR, Rossi F, Polverino M, Owen CA and D’Agostino B. Effects of sex hormones on bronchial reactivity during the menstrual cycle. BMC Pulm Med. 2014 Jul 1; 14(1):108. PMID: 24984749.  

14.       Polverino F, Doyle-Eisele M, McDonald J, Kelly EM, Wilder J, Royer C, Laucho-Contreras M, Mauderly J, Divo M, Pinto-Plata V, Celli BR, Tesfaigzi Y, Owen CA. A novel non-human primate model of cigarette smoke-induced chronic obstructive pulmonary disease. Am J Pathol 2015 Mar; 185(3):741-55. PMID: 25542772.

15.       Laucho-Contreras M*, Polverino F*, Petersen H, Pinto-Plata V, Kelly E, Divo M, Sood A, Miller B, Taj-Singer R, Pilon A, Stripp B, Tesfaigzi Y, Celli B, Owen CA. Protective role for club cell secretory protein-16 (cc16) in the development of COPD. Eur Respir J. 2015 Jun; 45(6):1544-56. PMID: 25700379. 

16.       Lao T, Glass K, Qiu W, Polverino F, Gupta K, Morrow J, Mancini JD, Vuong L, Perrella MA, Hersh CP, Owen CA, Quackenbush J, Yuan G, Silverman EK and Zhou X. Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring. Genome Med. 2015 Feb 14; 7(1):12. PMID: 25763110

17.       Polverino F†, Santoriello C, Andò F, Girbino G, Cappetta D, D'Agostino B, Vatrella A, Polverino M, Milic-Emili J. Recumbent deoxygenation in mild/moderate liver cirrhosis: the "clinodeoxia". The ortho-clino paradigm. Respir Med. 2014 Jul;108(7):1040-8.

18.       Polverino F, Cosio BG, Pons J, Laucho-Contreras M, Tejera P, Iglesias A, Rios A, Jahn A, Sauleda J, Divo M, Pinto-Plata V, Scholl L, Rosas IO, Agusti A, Celli BR, Owen CA. B-cell activating factor: an orchestrator of lymphoid follicles in severe COPD. Am J Respir Crit Care Med. 2015 Jun 13; 192(6):695-705. PMID: 26073875.

19.       Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nat Med. 2016 Feb; 22(2):163-74. PMID 26752519.

20.       Jiang Z, Lao T, Qiu W, Polverino F, Gupta K, Guo F, Mancini JD, Naing ZZ, Cho MH, Castaldi PJ, Sun Y, Yu J, Laucho-Contreras ME, Kobzik L, Raby BA, Choi AM, Perrella MA, Owen CA, Silverman EK, Zhou X. A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin. Am J Respir Crit Care Med. 2016 Jul 15;194(2):185-97PMID: 26862784. 

21.       Polverino F†, Laucho-Contreras M, Rojas Quintero J, Divo M, Pinto-Plata V, Sholl L, de-Torres JP, Celli BR, and Owen CA. Increased expression of APRIL in lung leukocytes and alveolar epithelial cells in COPD patients with non small cell lung cancer: A possible link between COPD and lung cancer? Multidiscip Respir Med 2016 Apr 4; 1:17. PMID: 27047662

22.       Schiavo A, Renis M, Polverino M, Iannuzzi A, Polverino F. Acid-base balance, serum electrolytes and need for non-invasive ventilation in patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease admitted to an internal medicine ward. Multidiscip Respir Med. 2016 May 25;11:23. PMID: 27226896. 

23.       Polverino F, Laucho-Contreras M, Petersen H, Bijol V, Sholl LM, Choi M, Divo M, Pinto-Plata V, Tesfaigzi Y, Celli B, Owen CA. A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in COPD. Am J Respir Crit Care Med. Jun 1;195(11):1464-1476. PMID: 28085500

24.       Cabrera López C, Casanova Macario C, Marín Trigo JM, de-Torres JP, Sicilia Torres R, González JM, Polverino F, Divo M, Pinto Plata V, Zulueta JJ, Celli B. Comparison of 2017 and 2015 Global Initiative for Obstructive Lung Disease: Impact on Grouping and Outcomes. Am J Respir Crit Care Med. 2017 Nov 3. PMID: 29099607

25.       Polverino F†, de Torres JP, Santoriello C, Capuozzo A, Mauro I, Rojas J, D’Agostino B, Pistolesi M, Celli B, Polverino M, Owen CA. Gas Exchange and Breathing Pattern in Women with Postmenopausal Bone Fragility. Respiratory Medicine. 2018 Apr;137:141-146. PMID: 29605198

26.       Wang X*, Polverino F*, Rojas-Quintero J, Zhang D, Sánchez J, Yambayev I, Lindqvist E, Virtala R, Djukanovic R, Davies DE, Wilson S, O'Donnell R, Cunoosamy D, Hazon P, Higham A, Singh D, Olsson H, Owen CA. A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD. Am J Respir Crit Care Med. 2018 Jun 4;198(12):1500-18. PMID: 29864380

27.       Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA. A Disintegrin and A Metalloproteinase Domain-8 (ADAM8): A Novel Protective Proteinase in COPD. Am J Respir Crit Care Med. 2018 2018 Nov 15;198(10):1254-1267. PMID: 29750543

28.       Laucho-Contreras ME*, Polverino F,* Rojas-Quintero J, Wang X, Owen CA. Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice. Physiol Rep. 2018 Aug;6(15):e13797. PMID:30084231

29.       De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR; Interdisciplinary Association for Research in Lung Disease (AIMAR) Study Group. Supplementation with Qter® and Creatine improves functional performance in COPD patients on long term oxygen therapy. Respir Med. 2018 Sep;142:86-93. PMID: 30170808

30.       Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Celli BR, Tesfaigzi Y. The Course of Lung Function in Middle-Aged Heavy Smokers: Incidence and Time to Early Onset of COPD. Am J Respir Crit Care Med. 2018 Aug 16. PMID: 30114375

31.       Pabón MA, Patino E, Bhatia D, Rojas-Quintero J, Ma KC, Finkelsztein EJ, Osorio JC, Malick F, Polverino F, Owen CA, Ryter SW, Choi AM, Cloonan SM, Choi ME. Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. JCI Insight. 2018 Sep 20;3(18). PMID: 30232271

32.       Tartaglione G, Spaziano G, Sgambato M, Russo TP, Liparulo A, Esposito R, Mirra S, Filosa R, Roviezzo F, Polverino F, D'Agostino B. Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness. Physiol Rep. 2018 Oct;6(20) PMID: 30370666

33.       Casanova C, Marin JM, de Torres JP, Torres RS, Gonzales JM, Polverino F, Divo M, Pinot-Plata V, Zulueta J, Callejas FJ, Celli B. Arch Bronconeumol. 2019. Distribution and prognosis following the new risk stratification criteria of the Spanish COPD guidelines. Arch Bronconeumol. 2019 Feb. 

34.       Polverino F, Lu B, Rojas J, Vargas SO, Patel A, Owen CA, Gerard NP, Gerard C, Cernadas M. CFTR regulates B cell activation and lymphoid follicle development. Respir Res. 2019;20(1):133. Published 2019 Jul 1. 

35.       Sullivan JL, Bagevalu B, Glass C, Sholl LM, Kraft M, Martinez FD, Bastarrika G, de-Torres JP, Estepar RSJ, Guerra S, Polverino F†. B cell adaptive immune profile in emphysema-predominant COPD. Am J Respir Crit Care Med. 2019. Dec 1;200(11):1434-1439

36.       Esposito R, Spaziano G, Giannattasio D, Ferrigno F, Liparulo A, Rossi A, Roviezzo F,  Sessa M, Falciani M, Berrino L, Polverino M, Polverino F,  D'Agostino B. Montelukast improves symptoms and lung function in asthmatic women compared with men. Frontiers in Pharmacology 2019, Sep 24;10:1094.

37.       Pinto-Plata V, Casanova C, Divo M, Tesfaigzi Y, Calhoun V, Sui J, Priolo C, Polverino F, Petersen H, de-Torres JP, Marin JM, Owen C, Baz R, Cordoba-Lanus E, Celli B. Plasma Metabolomics and survival differences in COPD patients. Resp. Res 2019. Oct 15;20(1):219.

38.       Polverino F †, Hysinger EB, Gupta N, Willmering M, Olin T, Abman SH, Woods JC. Lung MRI as a potential complementary differential diagnostic tool for early COPD. Am J Med. 2020 Jun;133(6):757-760.

39.       Kimura H, Francisco D, Conway M, Martinez FD, Vercelli D, Polverino F, Billheimer D, Kraft M. Type 2 Inflammation Modulates ACE2 and TMPRSS2 in Airway Epithelial Cells. J Allergy Clin Immunol. 2020 May 15:S0091-6749(20)30647-3.

40.       Polverino M, Capuozzo A, Cicchitto G, Ferrigno F, Mauro I, Santoriello C, Sirignano E, Aliverti A, Celli B, Polverino F†. Smoking Pattern in Men and Women: A Possible Contributor to Gender Differences in Smoke-related Lung Diseases. Am J Respir Crit Care Med. 2020 Oct 1;202(7):1048-1051.

41.       Cicchitto G, Capuozzo A, Cacace L, Cavallera A, Mauro I, Ferrigno F, Polverino F†. RP EBUS as a guide for transbronchial pulmonary biopsy in the diagnosis of Organizing Pneumonia. Multidisciplinary Respiratory Medicine 2020. Jul 1;15(1):658.

42.       Polverino F†, Stern DA, Ruocco G, Balestro E, Bassetti M, Candelli M, Cirillo B, Contoli M, Corsico A, D’Amico F, D’Elia E, Falco G, Gasparini S, Guerra S, Harari S, Kraft M, Mennella L, Papi A, Parrella R, Pelosi P, Poletti V, Polverino M, Tana C, Terribile R, Woods JC, Di Marco F, Martinez FD, on behalf of the ItaliCO study group. Comorbidities, cardiovascular therapies and COVID-19 Mortality: a Nationwide, Italian Observational Study (ItaliCO). Frontiers Cardiovasc Med 2020 Oct 9;7:585866.

43.       Divo M, Marin-Oto M, Casanova C, Cabrera C, deTorres JP, Marin JM, Hersh C, Ezponda, A, Maguire, C, Pinto-Plata V, Polverino F, Ross J, DeMeo D, Bastarrika G, Silverman E, Celli B. Somatotypes trajectories during adulthood and its association with COPD phenotypes. ERJ open research, 2020 Sep 14;6(3):00122-2020.

44.       Li Y, Zhang L, Polverino F, Guo F, Hao Y, Lao T, Xu S, Li L, Pham B, Owen CA, Zhou X. Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells. Sci Rep. 2021 Apr 27;11(1):9074.

45.       Johnson MD, Younis US, Menghani SV,  Addison KJ, Whalen J, Pilon AL, Cress AE, Polverino F, Romanoski C, Kraft M, Martinez FD, Guerra S, Ledford J. Binding of CC16 to a novel ligand, 41 integrin (VLA-4), is necessary for  protection during M. pneumonia infection. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1410-1418.

46.       Tomchaney M, Contoli M, Mayo J, Baraldo S, Shuaizhi L, Cabel CR, Bull DA, Lick S, Malo J, Knoper S, Kim SS, Tram J, Rojas-Quintero J, Kraft M, Ledford J, Tesfaigzi Y, Martinez FD, Thorne CA, Kheradmand F, Campos SK, Papi A, Polverino F†. Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease. BMC Pulmonary Medicine 2021 Aug 23;21(1):275.

47.       Polverino F†, Wu TD, Rojas-Quintero J, Wang X, Mayo J, Tomchaney M, Tram J, Zhang D, Cleveland KH, Cordoba-Lanus E, Owen CA, Fawzy A, Kinney GL, Hersh CP, Hansel NH, Doubleday K, Tesfaigzi Y, Ledford JG, Casanoca C, Zmijewski J, Konhilas J, Langlais PR, Schnellmann R, McCormack M, Celli B. Metformin: experimental and clinical evidence for a potential role in emphysema treatment. Am J Respir Crit Care Med 2021 Sep 15;204(6):651-666.

48.       Dieffenbach PB, Mallarino Haeger C, Rehman R, Corcoran AM, Coronata AMF, Vellarikkal SK, Chrobak I, Waxman AB, Vitali SH, Sholl LM, Padera RF, Lagares D, Polverino F, Owen CA, Fredenburgh LE. A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature. Am J Respir Crit Care Med. 2021 Sep 22. In press.

49.       Iannuzo N, Insel M, Marshall C, Pederson WP, Addison KJ, Polverino F, Guerra S, Ledford JG. Infect Immun. 2021 Nov 15:IAI0054821. CC16 deficiency in the context of early life Mycoplasma pneumoniae infection results in augmented airway responses in adult mice.

50.       Ezponda A., Casanova C, Divo M, Marín M, Cabrera C, Marín JM, Bastarrika G, Pinto-Plata V, Martin-Palmero A, Polverino F, Celli BR*, and de-Torres JP*. Chest-CT assessed comorbidities and all-cause mortality risk in COPD patients in the BODE cohort. Respirology, Jan 2022, In press.

51.       Yang CX, Tomchaney M, Landecho MF, Zamacona BR, Marin Oto M, Zulueta J, Malo J, Knoper S, Contoli M, Papi A, Vasilescu DM, Sauler M, Straub C, Tan C, Martinez FD, Bhattacharya D, Rosas IO, Kheradmand F, Hackett TL, Polverino F†. Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection. Cells. 2022 Jun 7;11(12):1864. 

52.       Divo M, Marin JM, Cabrera C, Pinto-Plata V, Marin-Oto M, Polverino F, de-Torres JP, Billheimer D, Celli BR. Comorbidities and Mortality Risk in Adults Younger than 50 years of age with Chronic Obstructive Pulmonary Disease. Respiratory Research, in press.

53.       Polverino F†, Mirra D, Esposito R, Spaziano G, Sgambato M, Piegari E, Cozzolino A, Cione E, Gallelli L, Capuozzo A, C. Santoriello, Berrino L, de-Torres J.P., Polverino M, D'Agostino B. Similar Programmed Death Ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer. Sci. Rep. 2022. In press

54.       Polverino F†, Stern DA, Snyder EM, Wheatley-Guy C, Bhatt SP, Martinez FD, erra S, Morgan WJ. Lower Respiratory Illnesses in Childhood are Associated with The Presence of Air Trapping in Early Adulthood. Resp. Med. 2022, In press.

55.       Pederson WP, Laurie M Ellerman LM, Sandoval EC, Boitano S, Frye JB, Doyle KP, Brooks HL, Polverino F, Ledford JG. Development of a Novel Mouse Model of Menopause-associated Asthma. Am J Resp Cell Mol Biol 2022. In press.

56.       Polverino F, Mirra D, Yang CX, Esposito R, Spaziano G, Rojas-Quintero J, Sgambato M, Piegari E, Cozzolino A, Cione E, Gallelli L, Capuozzo A, Santoriello C, Berrino L, de-Torres JP, Hackett TL, Polverino M, D'Agostino B.Sci Rep. 2022 Dec 27;12(1):22402. doi: 10.1038/s41598-022-26650-9. Similar programmed death ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer. PMID: 36575294.

57.       Rojas-Quintero J, Laucho-Contreras ME, Wang X, Fucci QA, Burkett PR, Kim SJ, Zhang D, Tesfaigzi Y, Li Y, Bhashyam AR, Zhang L, Khamas H, Celli B, Pilon AL, Polverino F*, Owen CA*. CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice. JCI Insight. 2023 Feb 14:e130771.

58.       Rojas-Quintero J, Ochsner SA, New F, Divakar P, Yang CX, Wu TD, Robinson J, Chandrashekar DS, Banovich NE, Rosas IO, Sauler M, Kheradmand F, Gaggar A, Margaroli C,  San Jose Estepar R, McKenna NJ, Polverino F. Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in COPD. Am J Resp Crit Care Med 2023. In press. 

59.       Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Hengstschläger M, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada L. SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells.. J.Sci Transl Med. 2023 Sep 13;15(713):eade2581.

60.       Tanyaratsrisakul S, Dy ABC, Polverino F, Numata M, Ledford JG. Myeloid-associated differentiation marker is associated with type 2 asthma and is upregulated by human rhinovirus infection. Front Immunol. 2023 Aug 11;14:1237683.

61.       Polverino M, Sampaolo S, Capuozzo A, Fasolino M, Aliberti M, Satta E, Santoriello C, Orengo JP, Polverino F. Respiratory Function Changes as Early Signs of Amyotrophic Lateral Sclerosis. Respiration. 2023;102(11):919-923. 

62.       Divo MJ, Liu C, Polverino F, Castaldi PJ, Celli BR, Tesfaigzi Y.From pre-COPD to COPD: a Simple, Low cost and easy to IMplement (SLIM) risk calculator. Eur Respir J. 2023 Sep 28;62(3):2300806.

1.         Polverino M, Santoriello C, Polverino F, Polverino E, Musella V, Fiorenzano G, Ando’ F. Clinical, radiological and functional diagnosis. In: Di Cioccio L, Stazi G, editors. COPD in the elderly.  Rome: Casa Editrice Scientifica Internazionale; 2005. P. 9-33.

2.         Santoriello C, Cicchitto G, De Rosa C, Polverino F, Andò F, Polverino M. Drug resistant bronchial asthma. Multidiscip Respir Med 2006; 1:69-71.

3.         Cicchitto G, Fiorenzano G, Adiletta G, Panariello L, Giordano S, Polverino F, Polverino M. Familiar pulmonary alveolar microlitiasis. Multidiscip Respir Med 2006; 3:88-91.

4.         Polverino F, De Sio V, Santoriello C, Giannattasio D, Polverino M. Allergic cough: diagnostic-therapeutic mismatch. Multidiscip Respir Med 2006; 2:87-88.

5.         Polverino F, Polverino M. Management of elderly with respiratory failure. Geriatr Med J 2007; 1(1): 21-22.

6.         Polverino F, Santoriello C, De Sio V, Musella V, De Rosa C, Cicchitto G, De Blasio F, Andò F, Polverino M. Recumbent hypoxemia “clinodeoxia” in cirrhosis: relationship with age-related trends of alveolar ventilation and right-to-left shunting. Multidiscip Respir Med 2007; 1:28-36.

7.         Santoriello C, Polverino F, Fiorenzano G, Polverino M. Pulmonary artery agenesis: morphologic and functional assessment. Multidiscip Respir Med 2007; 1:115-117.

8.         Polverino F, Santoriello C, De Sio V, Giannattasio D, Di Buono L, Cicchitto G, De Rosa C, Andò F, Polverino M. Tests of upper air way obstruction (UAO) predicted values and application in patients with extrathoracic UAO. Multidiscip Respir Med 2007; 2:22-29.

9.         Polverino F, Cicchitto G, De Sio V, Di Buono L, Fiorenzano G, Giannattasio D, Musella V, Santoriello C, Viggiano D, Polverino M. Predictors of childhood asthma onset and role of early prophylaxis. Multidiscip Respir Med 2007; 3:12-18.

10.       Polverino F, Polverino E, Polverino G, Polverino S, Polverino M. Advanced stages of COPD can be lifelong asymptomatic: a lesson of life. Multidiscip Respir Med 2008; 3.228- 231.

11.       Santoriello C, Musella V, Polverino F, Polverino M. Signs of “myocardial ischemic equivalents” without ECG alterations, observed at cardiopulmonary exercise test. Multidiscip Respir Med 2008; 1:87-89.

12.       Polverino F, Cosio BG. Subphenotypes: the many faces of chronic obstructive pulmonary disease. Therapy 2009; 6(6):771–773.

13.       Polverino F, Longhini F, Vanaudenaerde B, Bikov A, Aamli A, Singanayagam A, Kahn N, Boots A, Skoczynski S. Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice. Breathe (Sheff). 2015 Dec; 11(4):303-5. PMID: 27066124

14.       Laucho-Contreras ME, Polverino F, Tesfaigzi Y, Pilon A, Celli BR, Owen CA. Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opin Ther Targets. 2016 Feb; 11:1-15. PMID: 26781659

15.       Marin JM, Cote C, Casanova C, Pinto-Plata V, Montes de Oca M, Divo MJ, de Torres JP, Zulueta J, Cabrera C, Carrizo S, Polverino F, Celli BR; en representación del grupo BODE. Sumplifying the guidelines. The COPD 10 commandments. Arch Bronconeumol. 2016 Apr; 52(4):179-189. PMID: 26973024

16.       Polverino F, Seys LJ, Bracke KR, Owen CA. B cells in chronic obstructive pulmonary disease: moving to center stage. Am J Physiol Lung Cell Mol Physiol. 2016 Oct 1;311(4):L687-L695. PMID:27542809

17.       Polverino F†, Celli BR, Owen CA. Reply to Cigarette Smoke is an Endothelial Cell Toxin. Am J Respir Crit Care Med. 2017 Jul 20. PMID: 28726486

18.       Polverino F†, Celli BR, Owen CA. COPD: Breathing new life into old cardiovascular drugs? Annals of American Thoracic Society 2017. Sept 26. PMID: 28950067

19.       Polverino F, Celli BR, Owen CA. COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? Pulm Circ. 2018 Jan-Mar;8(1):2045894018758528. PMID: 29468936

20.       Polverino F†, Celli B. The Challenge of Controlling the COPD Epidemic: Unmet Needs. Am J Med. 2018 Sep;131(9S):1-6. Epub 2018 May 17. PMID:29778456

21.       Soriano JB, Polverino F, Cosio BG. What is Early COPD and Why is it Important? Eur Respir J. 2018 Oct 11. PMID: 30309976

22.       Polverino F†. Deconvoluting COPD: Are B-cells the frontrunners? Am J Respir Crit Care Med. 2019 Jan 11. In press.

23.       Polverino F†, Sam A, Guerra S. COPD: to be or not to be. That is the question. Am. J Med. 2019. In press.

24.       Polverino F†, Soriano J. Small Airways and Early Origins of COPD: Pathobiological and epidemiological considerations. Eur. Resp. J. 2020. In press. 

25.       Scoppetta C, Di Gennaro G, Polverino F. Editorial - High Dose Intravenous Immunoglobulins as a Therapeutic Option for COVID-19 Patients. Eur Rev Med Pharmacol Sci. 2020 May;24(9):5178-5179. 

26.       Polverino F†. Cigarette Smoking and COVID-19: A Complex Interaction. Am J Respir Crit Care Med. 2020 Aug 1;202(3):471-472.

27.       Polverino F† and Curtis JL. The ABCs of granulomatous lung diseases: age-associated B cells. Am J Respir Crit Care Med. 2020. Oct 1;202(7):922-924.

28.       Polverino F†, Balestro E, Spagnolo P. Clinical presentations, pathogenesis, and therapy of sarcoidosis: state of the art. Journal of Clinical Medicine 2020. Jul 24;9(8):2363.

29.       Polverino F†, Kheradmand F. COVID-19, COPD, and AECOPD: immunological, epidemiological, and clinical aspects. Front. Med. 2021 Jan 18;7:627278.

30.       Polverino F† and Soriano J. Asthma and COPD: Just Old Friends or Relatives? Am J Respir Crit Care Med. 2021 June 30. In press.

31.       Polverino F†. Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome. Eur. Resp. J. 2021. In press.

32.       Satta E, Calfarone E, De Maio A, Gentile S, Romano C, Polverino M, Polverino F†. Kidney and lung in pathology: mechanisms and clinical implications. Multidisc. Resp. Med. Jan 2022. In press.

33.       Polverino F†, Celli BR. Selecting the Right Patient: The Achille's Heel of COPD Clinical Trials. Am J Respir Crit Care Med. 2022 Jul 14. 

34.       Polverino F†, Washko GR, Covar RA, Hysinger EB, Hackett TL, Bhatt SP, Brusselle G, Dharmage SC. The low flyers: persistent airflow limitation in young adults. Lancet Respir Med. 2022 Jul 15:S2213-2600(22)00250-8.

35.       Polverino F†, Marin JM. The lower respiratory tract: the hot spot for chronic fixed airflow limitation. Eur Respir J. 2022. 

36.       Polverino F†, Celli BR. Challenges in the pharmacotherapy of COPD subtypes. Arch. de Bronc. 2022 Nov 19:S0300-2896(22)00631-7. In press

37.       Polverino F†. Am J Respir Cell Mol Biol. 2023 Feb 8. Genetic Susceptibility to COPD and IPF: The Missing Link. Am J Respir Cell Mol Biol. 2023 Feb 8. In press

38.       Polverino F†, Kalhan R.Am J Respir Crit Care Med. 2023 Aug 1;208(3):220-222. Leveraging Omics to Predict Chronic Obstructive Pulmonary Disease Exacerbations: The "Immunome". In press. 

39.       Tesfaigzi Y, Curtis JL, Petrache I, Polverino F, Kheradmand F, Adcock IM, Rennard SI.

Does COPD Originate from Different Cell Types? Am J Respir Cell Mol Biol. 2023 Aug 16. doi: 10.1165/rcmb.2023-0175PS. Online ahead of print. PMID: 37584669

40.       Bracke KR, Polverino F. Blunted adaptive immune responses and acute exacerbations of COPD: breaking the code. Eur Respir J. 2023 Aug 3;62(2):2301030.

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